Mab-Zap: A Tool for Evaluating Antibody Efficacy for Use in an Immunotoxin

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Mab-ZAP: a tool for evaluating antibody efficacy for use in an immunotoxin.

Immunotoxins, consisting of antibodies coupled to toxins, are extremely useful tools in the elimination of specific cell populations in vitro and in vivo for research and therapeutic applications. The antibody is used to target the toxin to a specific cell population, which is distinguished by its cell-surface antigen. Not all antibodies are suitable for creating an immunotoxin, and large numbe...

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ژورنال

عنوان ژورنال: BioTechniques

سال: 2000

ISSN: 0736-6205,1940-9818

DOI: 10.2144/00281pf01